Upon the virulence of the bacillus of bovine and human tuberculosis for monkeys / by Allan Macfadyen, M.D. Edin. (From the laboratory of the Lister Institute of Preventive Medicine.).

  • Macfayden, Allan, 1860-1907
Date:
[1903?]
Catalogue details

Licence: In copyright

Credit: Upon the virulence of the bacillus of bovine and human tuberculosis for monkeys / by Allan Macfadyen, M.D. Edin. (From the laboratory of the Lister Institute of Preventive Medicine.). Source: Wellcome Collection.

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    B.—Feeding Experiments. (a) With bovine tubercle bacilli.—1. Rhesus monkey. The animal was fed with about five cubic centimetres of the emulsified udder of a cow proved to contain tubercle bacilli. It died ten days after the feeding. The result was negative owing to premature death. 2. Rhesus monkey. The animal was fed with a small portion of the emulsified udder of a cow. The result was negative as death occurred in two days. 3. Rhesus monkey. The animal was fed with a small portion of a tuberculous udder and nine days subsequently received a second feed. It died 33 days after the first feeding. Post mortem the mesenteric glands were found to be caseating and there were nodules in the spleen and the liver. Tubercle bacilli were found in all the affected organs. No intestinal lesions could be detected. 4. Rhesus monkey. The animal was fed with an emulsion of bovine tuberculous glands and 14 days subsequently with a portion of a diseased udder. It died 35 days after the first feeding. Post mortem nodules were found in the spleen, the liver, and the lungs. The mesenteric glands were enlarged. Tubercle bacilli were found in the lesions. No tuberculous lesions were observed in the intestine. 5. Rhesus monkey. The animal was fed with tuberculous udder. A second and third feed of similar material was given seven and 12 days after the first. Death occurred 45 days after the first feeding experiment. Post mortem nodules were found in the spleen, the liver, and the lungs and the mesenteric glands were enlarged. There were no lesions in the intestine. Tubercle bacilli were found in the affected organs. 6. Rhesus monkey. The animal was fed with a small portion of affected cow’s lung and on the ninth and thirty- fifth days a second and third feed were given of similar material. Death followed 57 days after the first feeding. Post mortem general tuberculosis was found but there were no lesions in the intestine. 7. Rhesus monkey. The animal was fed with emulsified lesions of bovine lung. Only one feeding experiment was made. Death took place 65 days subsequently. Post