On the relative sizes of the organs of rats and mice bearing malignant new growths / by F. Medigreceanu ; [communicated by J. Rose Bradford].

  • Medigreceanu, Florentin.
Date:
1910
Catalogue details

Licence: In copyright

Credit: On the relative sizes of the organs of rats and mice bearing malignant new growths / by F. Medigreceanu ; [communicated by J. Rose Bradford]. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Table II. No. Age. Ratio : tumour- weight to body- weight. Digestive tract. Liver. Heart. Kidneys. Lungs. Spleen. Normal Rats.— Ratio of Organ-weight to Body-weight less Tumour. A. Usual Diet. 5 I 2-4 mo8. | - 1 1 : 19-7 | 1 : 19-9 | 1 : 180 | B. Special Diet. 1 : 94-6 | 1 : 140-3 | 1 : 132-4 9 I 2-4 „ | - 1 1 : 30-3 1 1 : 19‘9 j 1 : 205‘9 J 1—2 Days after Litter. 1 : 122-7 | 1 : 102 | 1 : 114-7 ^ 1 4* „ 1 — | 1 : 29-8 | 1 : 166 1 1 : 211*8 | 1 : 109’4 | 1 : 114‘4 | Negative Rat (20 days after the Tumour had disappeared). 1 : 1487 1 1 4 „ 1 - 1 1 : 29-3 1 1 : 156 | 1 : 198-8 | 1 : 103-7 | 1 : 74-8 | 1 : 145 2 3£-5 „ 1 : 1-6 1 : 24-7 1 : 11 1 : 1348 1 : 624 1 : 1163 6 3-4£ „ 1 : 36 1 : 24 2 1 : 132 1 : 158-6 1 : 67-2 1 : 110-6 Eats with Transplanted Tumours. Sarcoma. A. Usual Diet. 1 : 54-4 1 : 1151 B. Special Diet. 7|3-5„ 11:2 11: 28 9 | 1 : 12'1 | 1 : 138 I 1 : 611 | 1 : 99'4 | 1 : 101-4 Carcinoma. Usual Diet. 3 4-44 „ 1:8-2 1 : 24 8 1 : 14‘0 1 : 200-2 1 : 93 0 1 : 95 8 | 1 : 67'6 point, between the growth of the tumour and the weight of the liver, whether comparison is made between different tumours of the same strain, tumours of different strains, or spontaneous tumours. In a single case, and under exceptional circumstances, an aberrant result was obtained. A mouse with a tumour five months old, of strain “ 37,” weighed 19-5 grammes, while its tumour weighed 22'5 grammes. The liver was of normal weight; it is not possible to exclude the possibility that a stage of hypertrophy had been passed through. Since this case stands alone, undue weight cannot be laid upon it. The ratio of liver to “ body-weight plus tumour ” corresponds in the majority of cases with the normal values. Frequently, however, one finds, on the one hand, as e.g. with the rat-tumours (and also Tumour “ 39 ”), that the liver is too large in proportion to “bodyfweight plus tumour”; on jthe