An essay on the history, preparation, and therapeutic uses of iodine / by Samuel J. Hobson.

  • Hobson, Samuel J., -1882.
Date:
1830
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Licence: Public Domain Mark

Credit: An essay on the history, preparation, and therapeutic uses of iodine / by Samuel J. Hobson. Source: Wellcome Collection.

Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)

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    small quantities, acts as a slight stimulant, and produces vo- miting. 2nd. That in the dose of a drachm, it constantly kills in four or five days the dogs who have the oesophagus tied,* by slowly producing ulceration of the stomach. N 3rd. That in die dose of two or three drachms, when the oesophagus is not tied, it acts in the same manner upon ani- mals who do not vomit for several hours. 4th. That it rarely occasions death when it has been taken in the dose of one or two drachms, and the animals shortly af- ter throw it up by repeated vomiting. 5th. That it appears to act in the same manner upon man, as upon dogs. 6th. That it ought to be ranked among the corrosive poi- sons, t These facts show that Iodine induces the same train of phy- siological and pathological phenomena that all powerful irri- tants do when applied to the gastro-mucous surface. Majendie informs us, in his ** Formulary, that he introduced the tincture of Iodine into the veins of dogs without any ap- parent effect. We shall now cite a few cases where over-doses were taken together with their treatment and results. Dr. Gairdner informs us that a fine boy, aged ten years, did not live many hours after swallowing a tea-spoonful of the tincture of Iodine : and that a physician in London rashly prescribed it to the extent of ten grains at a dose I the patient, a young woman, was fortunately saved by vomiting.! We learn from Dr. Manson, of England, that a girl, aged seventeen years, who was taking Iodine for scrofula swallowed by mistake an ounce of the tincture, which, according to his formula, contains nearly half a drachm of Iodine : it was imme- diately rejected by emesis and no bad effect resulted.:(: * The operator passed a ligature around the oesophagus of some of the dog» after administering the Iodine, in order to prevent it from being ejected. t Gairdner oh Iodine. % Manson on Iodine.