Xerophthalmia, trigeminal degeneration and vitamin A deficiency / E. Mellanby.

  • Mellanby, Edward, Sir, 1884-1955.
Date:
[1934?]
Catalogue details

Licence: In copyright

Credit: Xerophthalmia, trigeminal degeneration and vitamin A deficiency / E. Mellanby. Source: Wellcome Collection.

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    ^OPHTHALMIA OF 6 DAYS’ DURATION OF RABBIT ON A-DEFICIENT DIET (figS. 7 to 10) Xerophthalmia of 3 weeks’ duration of rabbit ON A-DEFICIENT DIET (figS. 11 to 14) ig. 7.—Photograph of eye with xerophthalmia showing white film on cornea. I tg. 8.—Cornea. Keratinised layer can be I seen splitting away from supporting (epithelium. x 100. 9.—Cornea. Early epithelial changes of xerophthalmia. Note all cells flattened; nuclei of even surface cells still present. 450. mm * 10.—First branch of trigeminal nerve. 5 fane degenerating fibres ; modified Marchi. i C |e degeneration is less than is suggested by I e photograph as all the fibres shown are II longitudinally or obliquely. x 280. Fig, 11. — Photographs of eyes showing films, (a) thin and localised, (6) thick and widespread, 2 days later. Fig. 12.—-Cornea showing thick layer of keratinised epithelium, x 100. Fig. 13.—Cornea. No nuclei in most of epithelial cells (cf. fig. 9). x 450. Fig. 14.—First branch of trigeminal nerve, showing much degeneration; modified Marchi. Weigert preparations also showed degenerated fibres.