A text-book of organic chemistry / by A.F. Holleman ; edited by A. Jamieson Walker ; assisted by Owen E. Mott ; with the co-operation of the author.

  • Holleman, A. F. (Arnold Frederick), 1859-1953
Date:
1913
Catalogue details

Licence: In copyright

Credit: A text-book of organic chemistry / by A.F. Holleman ; edited by A. Jamieson Walker ; assisted by Owen E. Mott ; with the co-operation of the author. Source: Wellcome Collection.

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    atom with a hydrogenated pyridine-nucleus having the nitrogen atom linked to methyl. Heroin is the diacetyl-derivative of morphine. 414. Narcotine is present in opium to the extent of about G per cent., its percentage being next to that of morphine. It is crystal- line, melts at 170°, and is slightly poisonous. It is a weak tertiary base, its salts readily undergoing hydrolytic dissociation. It con- tains three methoxyl-groups, and has formula I. Nornarcotine has the formula Ci9Hi404N(0H)3. On hydrolysis, narcotine yields cotarnine (II.), a derivative of woquinoline, and the anhy- dride of meconinic acid, or meconin (III.): Narcotine, C22H23O7N. C CH CH C °C*Cfy\.CH3 O-OC.cf^01* CH CII2 C OCII3 I. Narcotine OCH3 C CHOH + CIIaO-Ci^CH CH CII2 C OCHa II. III. Cotarnine Meconin Bromine converts narcotine into dibromopyridine.