Differential diagnosis of syphilitic and non-syphilitic affections of the skin, including tropical diseases : a survey for medical practioners and students / by George Pernet.

  • Pernet George.
Date:
1904
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Licence: In copyright

Credit: Differential diagnosis of syphilitic and non-syphilitic affections of the skin, including tropical diseases : a survey for medical practioners and students / by George Pernet. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    THE BLOOD congenital syphilis: lungs, pancreas, kidneys, the adrenals, thymus, and so forth, but these would only be available after death. They should be examined in fatal cases, where the skin lesions and other signs were but slightly marked or anomalous. Epiphysitis syphilitica (Osteo-chondritis syphi- litica) affords confirmatory evidence in some cases. The epiphyses usually affected are those of the lower end of the femur, the upper end of the tibia, and the lower end of the radius ; but the other long bones are also liable to suffer. The epiphysis may become separated and suppuration occur as a result of secondary infection, and lead to helplessness of the affected part (hence so-called pseudo-paralysis). The elbow-joint on one side is the most usual seat of this condition. Dactylitis and onychitis may also be observed as concurrent symptoms. Iritis is also seen in congenital syphilis, just as it is in the acquired form, but in my experience it is very uncommon, although I have looked for it in many cases. It is well, however, to examine the eyes in a routine way, as unless specially sought for it may be overlooked owing to the mildness of the local symptoms as compared with what is observed in adult syphilitic iritis. It has been shown that the pupils of infants do not respond readily to atro- pine and homatropine, so that the existence of adhesions must not be too precipitately diagnosed. The blood also undergoes changes, leading to a condition of secondary anaemia. There is a diminu- tion in the number of red blood-corpuscles and in