The morbid effects of the retention in the blood of the elements of the urinary secretion / by William Wallace Morland.

Date:
1861
Catalogue details

Licence: Public Domain Mark

Credit: The morbid effects of the retention in the blood of the elements of the urinary secretion / by William Wallace Morland. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

    89/128 (page 83)
    may be a local hypermmia, although the general state of the system may be anaemic. This explanation of the difficulty is merely suggested as possible, not enunciated as certain; it nevertheless derives confirmation from the recent ob- servation of Dr. Garrod that uric acid is present in the serum, effused when a blister has been applied over a joint affected with gouty inflammation.” (Op. cit., English edition, 1856, p. 143.) Aside from the force of the evidence ad- duced by Dr. Garrod in the test referred to by Dr. Barlow, we cannot think the position of the latter author is strengthened by the analogy which he attempts to establish—or the similarity which he would imply, in vital action—between local hyperaemia in general anaemic states and the deposition of urate of soda by elective affinity. In fine, in the one case, the blood, although deteriorated, does not, in the circumstances proposed, contain a poison ; whereas, in the latter case, it does, or the local manifestations thereof would not occur. Mere local hyperaemia, occurring as above mentioned, cannot be properly compared with the local exhibition, by vicarious action, of the product of an abnormal amount of uric acid in the blood.