The 80-year-old children.

This documentary is about the only known family of siblings alive who all have the premature ageing condition, progeria. The five siblings live in an Indian village and were discovered by doctors in Calcutta. Throughout the programme we see various experts in the condition assess the siblings in an attempt both to help them and to get a greater understanding of the genetic structures that bring about progeria. As such, the programme contains much medical information and x-ray footage of the children's bodies as well as accounts of the latest research into finding the gene for progeria from Francis Collins, Director of the Human Genome Institute.