On the artificial production of tubercle in the lower animals : a lecture delivered at the Royal College of Physicians, May 15, 1868 / by Wilson Fox.

  • Fox, Wilson.
Date:
1868
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Licence: Public Domain Mark

Credit: On the artificial production of tubercle in the lower animals : a lecture delivered at the Royal College of Physicians, May 15, 1868 / by Wilson Fox. Source: Wellcome Collection.

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    Fig. 3.—Transverse Section of a Pulmonary Artery, surrounded by a growth of Tubercle. The outlines of the perivascular sheath are here obliterated, and the structure of the wall has become indistinct, (a) artery; (6) masses of nucleated cells and nuclei surroimding the vessel; (c) fusiform cells mingled with the growth; {d d) lines of fusiform cells surrounding the capillaries ; (e) a capillary obliterated ; and (/) another capillary obliterated, with enlarged nuclei in its walls. x 700 diam. Fig. 4.—Shows the gradual Thickening of the Walls of the Alveoli surrounding a Tubercular Granula- tion. The gradual obliteration of the tumen of the air-vesicles is distinctly seen. X 100 diam.; binocular arrangement. (Guinea-pig.) Fig. 5.—Enlargement of Nuclei of Capillaries of Lung preceding their obliterations, x 700 diam. (Guinea-pig.) Fig. 6.—Enlargement of Nuclei of Capillaries of Lung. Failure of injection. X 700 diam. (Guinea- Pig-) Fig. 7.—Growth of Masses of Nucleated Cells around Capillaries in Walls of Alveoli of Lung at margin of a mass of Tubercle. At («a) a denser mass of tubercle, with capillaries partially obliterated, x 700 diam. (Guinea-pig.) Fig. 8.—Growth of Fusiform Cells around Capillaries of Air-vesicles. x 700 diam. (Guinea-pig.) PLATE III. Fig. 1.—Omentum of Guinea-pig. Tubercle around a small artery (a), which bifurcates into two branches ib b). The tubercle is seen to consist of a mass of nucleated cells, and of nuclei around which no outer cell wall is visible. These which are more closely agglomerated around the vessel become more scattered at greater distances. The meshes of the omentum become gradually obliterated by the growth. Some large nucleated cells are seen among the growth. X 700 diam. Fig. 2.—Omentum of Guinea-pig. Masses of tubercles situated on the vessels (a h), a small artery and attendant veins. The growth of cells can be seen in places extending along the vessels for some distance from the larger masses. The extension into the neighboui'mg tissue of the omentum can also be observed. X 100 diam. (reduced). Fig. 3.—Omentum of Guinea-pig. Small mass of tubercle, having no apparent connexion with vessels. The thickening and filling of the meshes of the omentum with cells and nuclei can be seen here, as in Fig. 1. x 700 diam. Fig. 4.—Tubercle of Liver (Guinea-pig), {a a a a) Acini of liver, (b b) Bile ducts, marked by columnar epithelium, (c c) Growth of tubercle, which extends in all directions between the acini, 2)ressing them aside, (d d d) Spots where the tubercular growth is passing between the cells of the acini separating these, (e e) Isolated liver cells, left unchanged amid the growth of the tubercle, x 100 diam. Fig. 5. A, B.—Isolated portions of the Tubercular Growth in the Liver, x 700 diam. A. Shows nucleated cells imbedded in the meshes of a tilirous network. B. A mass of nuclei forming a string or obliterated tube. Fig. 6.—Portion of Subcutaneous Tissue amid Granulations near seat of injury, showing a multiplication of oval, round, and fusiform cells in the fibrous tissues. At (a a a) is a dense mass of nuclei, forming an irregular string or cord, x 700 diam. Fig. 7.—Isolated Cells, from margin of Fig. 6. The larger cells measure l-800th x 1-lOOOth of an inch. Fusiform cells are seen in process of division. X 700 diam. Fig. 8.— Section of a Subcutaneous Granulation, near seat of injury. Shows nucleated cells imbedded in the meshes of a fibrous network, x 700 diam.