Volume 1

Companion to the latest edition of the British pharmacopoeia : comparing the strength of the various preparations with those of the United States and other foreign pharmacopoeias to which are added not official preparations and practical hints on prescribing / by Peter Squire.

  • Squire, Peter.
Date:
1890-
Catalogue details

Licence: Public Domain Mark

Credit: Companion to the latest edition of the British pharmacopoeia : comparing the strength of the various preparations with those of the United States and other foreign pharmacopoeias to which are added not official preparations and practical hints on prescribing / by Peter Squire. Source: Wellcome Collection.

    69/670 (page 23)
    ACIDUM NITRICUM. NITRIC ACID. Syn. Azotic Acid. Colourless. Contains 70 per cent, by weight of real Acid, HN03, eq. 63. Tests.—Sp. g. 1-420. Boiling Point 250° F. (121° C.). 90 grains by weight, mixed with half an ounce of Distilled Water, require for neu- tralization 1000 grain-measures of the volumetric Solution of Soda. When evaporated to dryness, it leaves little or no residue. If it be poured upon copper filings, dense red fumes are formed. Diluted with six volumes of Distilled Water, it gives no precipitate with Chloride of Barium or Nitrate of Silver—indicating absence of Sulphuric and Hydrochloric Acids. 5 measures of Acid, sp. g. 1*500, and 2 of Water mixed, condense into 6^ measures, and make the sp. g. 1*420. (Austr., sp. g. 1-300; Belg., sp. g. 1-330; Dan., jSTorw., and Swed., sp. g. 1-180; Dutch, sp. g. 1-317; Fr., sp. g. 1-390; Ger., sp. g. 1-185; Hung. sp.g. 1-310; Pott., sp. g. 1-300—1-330 ; Russ. sp. g. 1200; Span., sp. g. 1-321; Swiss, sp. g. 1-130; U.S. sp. g. 1-420.) Medicinal Properties.—It is strongly corrosive, and is applied as a caustic to warts, phagedenic sores and chancres by means of a pointed glass rod. When diluted it is refrigerant, tonic, and antiseptic ; and if very much diluted forms a drink in febrile diseases, and is used also as an injection in phosphatic calculus. The diluted Acid is useful in diarrhoea. Thirty minims in ten ounces of Water is an excellent lotion for bleeding piles (Ringer). Incompatibles.—Alcohol, Alkalies, Oxides, Sulphate of Iron, Acetate of Lead, all Carbonates and Sulphurets. Antidotes.—In case of poisoning by Nitric Acid, the antidotes are Chalk, Mag- nesia, or Carbonated Alkalies, with White of Egg, Carron Oil, or Soap-suds, fol- lowed by Enemata of Beef Tea and Brandy, with Tinct. of Opium to prevent collapse; emollient drinks. Used in the preparation of Acidum Nitrohydrochloricum Dilutum, Acidum Phos- phoricum Concentratum, Argenti Nitras, Bismuthi Carbonas, Bismuthi Subnitras, Eydrargyri Oxidum Rubrum, Liquor Ferri Pernitratis, Liquor Hydrargyri Nitratis Acidus, Piloc:;rpinae Nitras, TJnguentum Hydrargyri Nitratis. Preparation. ACIDUM JSTITHXCTJM DILUTUM. Nitric Acid, 6 ; Distilled Water sufficient to make the mixture, when cooled to 60° F. (15-5° C), measure 31 ; or 2400 grains by weight of Acid, and Distilled Water sufficient to measure 20 oz. when cooled to 60° P. (15-5° C.) Colourless. Contains 17'44 per cent, of real Acid. Test.—Sp. g. 1*101. Six fluid drachms (361-3 grains by weight) require for neutralization 1000 grain-measures of the volumetric solu- tion of Soda, corresponding to one molecular weight in grains (63) of real Acid, HN03. Dose.—10 to 30 minims diluted with Water. For children 1^ min. 5 minims contain about 1 minim of strong Acid. Prescribed with bitter infusions and Tincture of Orange. Infusion of Roses made with this Acid, instead of Sulphuric Acid, and sweetened, is the most elegant form