Volume 1

Report on horse surra / by Alfred Lingard.

  • Lingard, Alfred.
Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: Report on horse surra / by Alfred Lingard. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

    52/892 (page 32)
    QO O u An Urticarial eruption appeared forty-eight hours after the first appearance of the haematozoon in the blood and persisted for twelve hours. The continued type of fever accompanied by remissions appeared on the second day, and was followed by an intermission on the fourteenth, and by death on the seventeenth day of the disease. Extensive pathological lesions were found invading the walls of the heart externally and internally. IIoi 'se No. XXXIV.—Was inoculated subcutaneously on the 2nd August 1881, with DO c.c. of blood taken from the Internal Jugular Vein of Horse No. XXXI. The latent period was twelve days. The temperature remained sub-normal until after the appearance of the haematozoon in the blood for the first time. It then rose 2vuC. in eighteen hours. The animal only survived the appearance of the organism twenty-seven hours, death on August 15th. Exten- sive pathological lesions were found involving the heart and other organs together with tire presence of a considerable quantity of fluid in the lateral ventricles of the brain. Horse No. XXXVIII—Was subcutaneously inoculated on the 26th August 1891, with EG o.c. of blood taken from the heart of Horse No. XL, nine and half hours post mortem. The latent period occupied nine days. The rise of temperture in this case was peculiar in that, although it followed for a few days the usual zig-zag course, increasing OWC. per day, it wras characterized by a morning exacerbation and evening remission, until the sixth day of the disease, when an apyrexial period occurred lasting four days. Between the ninth and thirty-fifth days of the disease, alternate fever and fever-free periods existed, the fever attaining a minimum in the morning or at midday and beijng generally followed in the night by a sudden fall of from 2°C. to 3°C. and finally during the last night days being again accompanied by fever of a remittent type, with ex- acerbations and remissions. This animal developed kidney complications charac- terized by the presence of albumen and epithelial casts in the urine and later by granular and hyaline casts. The urine remained alkaline until seven days before death, when it became respectively faintly alkaline, neutral, acid and finally strongly acid. Death occurred on the 16th October 1891, Cheyne-Stokes respira- tion being present for a short time before it occurred. Extensive pathological lesions wrere observed in the heart, with complete absence of any in the stomach, and of parasites from the intestinal tract. Horse No, XL,—Was subcutaneously inoculated at noon on 15th August 1891, with 0'6 c.c. of blood taken from the Internal Jugular Vein of Horse No. XXXIV, one and a quarter hours p.m. Sixty-eight hours later, an Urticarial eruption broke out. It persisted for 74 hours and then commenced to fade after the haematozoon appeared in the general circulation. The latent period occupied six days. Decrease in size of the tumour at the seat of inoculation and the simultaneous appearance of the organism in the blood. Temperature sub-normal until the presence of the haematozoon, when it rose and followed the continued type of fever with remissions until death on the 6th day. Autopsy.—Patches of congestion involving the mucous membrane of the villous portion of the stomach, also three small circular ulcers, undergoing the process of healing and a female specimen of Ascaris megalocephala in the same cavity, also lesions involving the heart, lungs, &c. Horse No. XLI.—Was subcutaneously inoculated on 26th August 1891 with l-0 c.c. of blood taken from the heart of Horse No. XL nine and a half hours post mortem. On the following morning an eruption of Urticaria broke out and persisted for thirty-six hours and then commenced to fade, i,e., five days previous to the first appearance of the organism in the blood. The latent period occupied seven days. The temperature remained sub-normal and normal the whole time, varying between 35‘3°C. and 37’3°C. The pathological lesions wrere slight. Horse No. XLVI.—Vricle Eat Surra, Vol. II. Horse No. XLVIII.—Vide Rat Surra, Vol. II. Horse No. L.—Was inoculated subcutaneously on the 15th October 1891 with 2’0 c.c. of blood serum taken from the Internal Jugular Vein of Horse No. XXXVIII, forty-five minutes postmortem. There was a gradual rise in the temperature until the evening of the fifth day following inoculation and by the