A guide to therapeutics / by Robert Farquharson.

  • Farquharson, Robert, 1836-1918.
Date:
1883
Catalogue details

Licence: Public Domain Mark

Credit: A guide to therapeutics / by Robert Farquharson. Source: Wellcome Collection.

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    tendency to migrate through the walls of the capillaries under inflammatory condi- tions. It also prevents, in some degree, the due giving up of oxygen by the red corpuscles, and may thus interfere with the oxygenation of the tissues. III. Respiration and Tem- perature.—No influence on the respiratory function has been observed. On the tem- perature of a person in full health but little lowering effect is produced; when fever is present, however, the tempe- rature may be brought clown by giving large doses. Opiuions differ so much as to the expla- nation of this effect, that it is impossible to speak with any confidence on the question. from the capillaries, and their subsequent transformation into pus-cells. Quinine may there- fore be of great service in localised inflammations, and in checking exhausting discharges from abscesses or wounds; and in pyaemia good results have followed its use. III. The antipyretic pro- perties of quinine are much prized in Germany, and it is there largely used in the treat- ment of typhus, typhoid, acute, rheumatism, and pneumonia. Immense doses, even reach- ing 75 grains, have been given, and it is observed that tole- rance of the drug is undoubt- edly present in fever, and that very much larger quantities can be taken than in a state of health. It is only when very freely given, however, that it has any cooling in- fluence ; and we are advised to prescribe from 25 to 45> grains in divided doses within the first half-hour, and then allow an intermission of from 24 to 48 hours, as the effect would be diminished by spread- ing it over a longer time, on account of its rapid elimina- tion. On account of this rapid elimination, Liebermeister con-