Note on the morbid anatomy of hypertrophic cirrhosis of the liver / by Robert Saundby.

Date:
1879
Catalogue details

Licence: Public Domain Mark

Credit: Note on the morbid anatomy of hypertrophic cirrhosis of the liver / by Robert Saundby. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    and distinctly cirrhosed. The appearances seen in sections of this liver (PI. XVII, fig. 1) are quite as good examples of newly developed biliaiy canalicuU as have been figured by any of the authors quoted. In another section tbe direct continuity of the newly-formed ducts with the rows of hepatic cells may he traced. This last case seems to be convincing proof that the network of newly-formed bjliary canahculi cannot be regarded as characteristic, even in its most pronounced condition, of the cirrhosis of biliary origin, described by MM. Hanot and Charcot as hypertrophic cirrhosis with jaundice; while the first case seems to indicate that very little alteration of the ducts may be present in a liver which conforms in all other respects to that type. In M. Hayem’s cases, previously alluded to, no alteration of the canaliculi is referred to in the text or indicated in the plates, so that in his cases, also, which appear to me, although M. Hanot disputes this, to have been cases of biliary cirrhosis,^ the “ fundamental phenomenon” was absent. The above communication was written early in 1878, but I did not have an opportunity of laying it before the Society till Eeb- ruary, 1879. I am now enabled to quote in support of my views a paper by Dr. Ludwig Bdeger,^ in which he describes the multi- plication of biliary canaliculi as present in cases of undoubted alcoholic cirrhosis, in the cirrhotic livers of tubercular patients and in some forms of atrophic nutmeg liver. February 18^^, 1879. 1 M. Hayem’s first case dated his illness from jaundice and dysentery,” fifteen years before, and on admission “ there was a yellow straw-coloured sub- icteric colour of the skin,” though there was no bile in the urine. The second case had been “ attacked by jaundice for some months ” before admission, and the urine contained a little bile-pigment, which, however, passed off. 2 “Beitrage zur Lehre von der Fibrosen Hepatitis,” ‘Virchow’s Archiv,* Band Ixxv, Heft. 1. 2