Notes of three cases of acute yellow atrophy of the liver / by Dyce Duckworth, M.D. and J. Wickham Legg, M.D.

  • Duckworth, Dyce, Sir, 1840-1928.
Date:
[cbetween 1800 and 1899?]
Catalogue details

Licence: Public Domain Mark

Credit: Notes of three cases of acute yellow atrophy of the liver / by Dyce Duckworth, M.D. and J. Wickham Legg, M.D. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

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    substance of the liver, and to be mixed with healthy coloured liver substance. The acini were still quite distinct. The knife was rendered distinctly greasy. In the left lobe there was a light yellow staining of the whole liver substance, and no distinction of acini could be made out. The spleen was soft; pulp and follicles natural. Microscopical Examination of the Liver and Kidneys.—Por- tions of the right and left lobes of the liver and of both kidneys were hardened in chromic acid. In the sections from the left lobe of the liver no trace of acini could be detected when viewed with a low power ( x 80). The section was extremely dark, but the dark material seemed equally distributed. On examining with a higher power ( x 270) no trace of liver cells could be found: the sections showed only an extremely dark and granular appearance, with large and small globules of fat and balls of pigment about the size of a granulation corpuscle. In the sections from the right lobe, a few hepatic cells remained undissolved, but in other respects the appearances were iden- tical with those of the left lobe. No crystals of any kind were observed. The tubules of the kidney were filled with a dark granular material, looking quite black by transmitted light: only here and there were a few epithelium cells discovered, and these were filled with granules and fat. Case II. (Notes by Mr. Cheyne, Clinical Clerk.) E. P., ajt. 23, a metal worker, was admitted into Radcliffe ward on August 23, 1870, under Dr. Duckworth's care. Is a short and slightly built man, with brown hair, and anemic, jaundiced complexion. Skin moist. No itching. Lies most comfortably on his back or on his left side. The conjunc- tive are pallid and icteric, pupils dilated. Thin sordes upon lips. Tongue covered all over with thin white fur. Pulse 116, of small volume and feeble. The chest is hyper-resonant, and no cardiac dullness is elicited by percussion. There is epigastric pulsation, and the sounds of the heart are more loudly heard in this situation than at the left nipple. Kespiration natural. The liver dullness measures three inches vertically in the right mamillary line. The urine cannot be procured, but the patient's linen is seen to be stained with bilious marks. The motions are pale. There is anorexia, but no sickness to-day. History.—patient was compelled to give up his work on the i7th inst. owing to pam in liis chest and umbilical