Heredity in ophthalmology / Jules François.

  • François, J. (Jules)
Date:
1961
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Heredity in ophthalmology / Jules François. Source: Wellcome Collection.

    12/750 (page 8)
    s CONTENTS Chapter Seven MUTATION.... 61 What Are the Causes of Mutation? 61; What is the Frequency of Spontaneous or Apparently Spontaneous Mutations in Man? 61; Can One Decide the Period When a Mutation Has Arisen Within a Given Family? 62. Chapter Eight VARIED PHENOTYPICAL MANIFESTATIONS OF THE GENE 63 Penetrance of the Gene, 63; Expressivity and Specificity of the Gene, 64; Age at Which the Hereditary Disease Appears, 66; Sex-Limited or Sex-Controlled Inheritance, 66; Irregular Dominant Heredity, 67. Chapter Nine BIFACTORIAL AND PLURIFACTORIAL INHERITANCE (DIMERISM AND POLYMERISM) 68 Chapter Ten MULTIPLE ALLELOMORPHS (POLYALLELISM) 71 Chapter Eleven HEREDITY AND ENVIRONMENT 74 Chapter Twelve THE STUDY OF TWINS 76 Chapter Thirteen ELEMENTS OF STATISTICS AND BIOMETRY 79 Elementary Concepts, 79; Gauss's Law and the Binominal Curve, 79; Standard Error, 80; Pearson's Test, 83; Biometry and Heredity, 84. PART II GENETICS IN OPHTHALMOLOGY Chapter Fourteen CLINICAL VARIETIES OF INHERITED DISEASES 97 Congenital Defects, 98; Abiotrophies, 99; Phakomatoses or Neuroectodermal Dysplasias, 100; Malignant Tumors, 100; Endocrine Disturbances, 100; Meta¬ bolic Disturbances, 100; Functional Abnormalities, 100; Syndromes, 101. Chapter Fifteen CARRIERS OF GENES AND THEIR DETECTION IN OCULAR PATHOLOGY 102 Individuals Heterozygous for an Incompletely Recessive Gene, 103; Individuals Carrying a Dominant Gene of Delayed Manifestation, 108; Carriers of a Gene of Incomplete Penetrance or Feeble Expression, 110.