Eosinophilia associated with hydatid disease / by C.G. Seligmann and L.S. Dudgeon.

  • Seligman, C. G. (Charles Gabriel), 1873-1940.
Date:
[1902]
Catalogue details

Licence: In copyright

Credit: Eosinophilia associated with hydatid disease / by C.G. Seligmann and L.S. Dudgeon. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    On admission into St. Thomas’s Hospital on Dec. 24th, 1901, her temperature was 101'2° F. By the evening of the 26th it had fallen to normal and remained so till Jan. 10th. There were enlargement of the right lobe of the liver and friction in the right axilla which suggested to Dr. Mackenzie the possible presence of hydatid disease. The patient’s blood was examined on Dec. 27th at 11 A.M., about two hours after her last meal and gave the following results : Red cells, 6,290,625 per cubic millimetre ; haemo- globin, 70 per cent. ; colour index, about 0-6 ; and white cells, 17,000 per cubic millimetre. A differential count of 500 white cells was as follows : polymorphonuclear neutro- philes, 22 per cent. ; eosinophiles, 57 per cent. ; lymphocytes, 20 per cent. ; and basophiles, 1 per cent. An operation was performed on Jan. 10th when 10 ounces of clear fluid, which contained hydatid hooklets, were with- drawn from a cyst in the right lobe of the liver. The next day her temperature rose to 102 5° at midnight and con- tinued to rise to this height nightly with morning remissions until the 18th. A second examination of the blood was made on the 13th. It showed 7000 leucocytes per cubic millimetre. A differential count showed: polymorphonuclear neutrophiles, 58 8 per cent. ; eosinophiles, 12 per cent.; lymphocytes, 28 2 per cent. ; and basophiles, 1 per cent. On the 16th it was noticed that the discharge from the cyst was copious and offensive and two days later it was purulent. At this time the temperature became normal for a couple of days ; it then rose, and though fluctuating considerably for the next month, it was, on the whole, constantly high at night. Further hydatid cysts were evacuated through an incision in the right fifth intercostal space. A differential blood count was made on Feb. 20th, with the following results : polymorphonuclear neutrophiles, 60 per cent. ; eosinophiles, 1 per cent. ; lympho- cytes, 29 4 per cent. ; and basophiles, 0 6 per cent. At this time there was a considerable amount of purulent material draining