Immunoglobulins.

London : University of London Audio-Visual Centre, 1974.

1 encoded moving image (42.41 min.) : sound, black and white.

00:42:41

University of London

Unrestricted

CC-BY-NC

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

In English

Presented by Dr Malcolm Turner, Institute of Child Health. Produced by Peter Bowen and David Sharp. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.

Segment 1 Turner introduces the subject of immunoglobulins and briefly traces the history of their discovery. He then lists the five proteins belonging to the immunoglobulin system. Time start: 00:00:00:00 Time end: 00:05:15:16 Length: 00:05:15:16

Segment 2 Turner describes the biological characteristics of immunoglobulins. Time start: 00:05:15:16 Time end: 00:10:37:00 Length: 00:05:21:09

Segment 3 Turner refers specifically and in detail to the work of Professor Rodney Porter who did much work investigating the immunoglobulin structure. He shows examples from Porter's research. Time start: 00:10:37:00 Time end: 00:19:52:00 Length: 00:09:15:00

Segment 4 Turner discusses the Bence Jones protein and refers to diagrams to explain how it works. Time start: 00:19:52:00 Time end: 00:24:34:11 Length: 00:04:42:11

Segment 5 Turner shows X-rays of Fab fragmentsand explains their function. Time start: 00:24:34:11 Time end: 00:29:45:19 Length: 00:05:21:08

Segment 6 Turner talks about the IgG subclasses and explains their function. Time start: 00:29:45:19 Time end: 00:34:16:00 Length: 00:04:32:06

Segment 7 Turner discusses mast cells and explains their function. Time start: 00:34:16:00 Time end: 00:38:19:11 Length: 00:04:03:11

Segment 8 Turner gives a full account of the polypeptide structure of human IgE, then summarises the lecture. Time start: 00:38:19:11 Time end: 00:42:41:11 Length: 00:04:22:00